A DYNAMIC MODE OF MITOTIC BOOKMARKING BY TRANSCRIPTION FACTORS

A dynamic mode of mitotic bookmarking by transcription factors

During mitosis, transcription is shut off, chromatin condenses, and deva curl arc angel most transcription factors (TFs) are reported to be excluded from chromosomes.How do daughter cells re-establish the original transcription program? Recent discoveries that a select set of TFs remain bound on mitotic chromosomes suggest a potential mechanism for

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Global evolution of the tumor microenvironment associated with progression from preinvasive invasive to invasive human lung adenocarcinoma

Summary: To investigate changes in the tumor microenvironment (TME) during lung cancer progression, we interrogate tumors from two chest computed tomography (CT)-defined groups.Pure non-solid metabo 15-gauge finish nailer cordless (pNS) CT density nodules contain preinvasive/minimally invasive cancers, and solid density nodules contain invasive can

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